Take it when you want an aggressive, melee-forward Destroyer army that hits far above its weight and want the whole force β not just Destroyers β to snowball in Strength as units die. It rewards a proactive, board-pushing playstyle over slow attrition, and it pairs strongly with a fast 1-DP support at 2,000 points. It's generally the preferred Necron Destroyer detachment over Annihilation Legion.
Sample gameplan: deploy a Destroyer-heavy core (Skorpekh and Ophydian for melee, Lokhust for range) plus an Overlord with the Destroyer Ankh. Use speed and deep strike to threaten multiple targets, then, in the first combat each turn, cleanly destroy or break an enemy unit with a Destroyer to flip on the army-wide +2 Strength. Use Methodical Murder before a key swing, Image of Death to protect an exposed unit, Unnatural Aggression to counter-charge, and Mortis Protocols to keep the grind going.