All four are legal and all four cost exactly 3 Detachment Points. What separates them is whether the 2 DP detachment's rule reaches your assassins, and the answer is the same for three of them and different for one.
1. Plus [Imperialis Fleet](/40k/armies/imperial-agents/detachments/imperialis-fleet). The only one where both rules reach both halves.
At all Costs is gated on AGENTS OF THE IMPERIUM, which is the faction keyword every model in the army carries, assassins included. So nominating an enemy unit with Eliminate At All Costs gives your Vindicare +1 to hit against it while Prime Target re-rolls its Wound rolls of 1, and nominating an objective with Acquire At All Costs puts your Callidus on it with a 5+ invulnerable save and +1 Objective Control. No other pairing does that.
2. Plus [Ordo Malleus, Daemon Hunters](/40k/armies/imperial-agents/detachments/ordo-malleus-daemon-hunters). The cleanest division of labour.
Destroy the Daemonic reaches INQUISITOR, INQUISITORIAL AGENTS and ORDO MALLEUS models, and assassins carry none of those keywords. So the two rules cover disjoint halves. That is not a waste: it means your Inquisition core gets an unconditional Hit roll of 1 re-roll in every phase while your assassins get a second use of their signature abilities, and neither rule is doing redundant work.
3. Plus [Ordo Xenos, Alien Hunters](/40k/armies/imperial-agents/detachments/ordo-xenos-alien-hunters). The one that fixes a real weakness.
Deathwatch Mission Tactics is powerful for three turns and absent for two, and it reaches DEATHWATCH units only. A Deathwatch firing line is also poorly placed to reach an enemy character hiding in a bodyguard unit. Prime Target's Warlord clause and the Vindicare's Shieldbreaker cover exactly that gap, and they work on the two turns your Mission Tactics are not.
4. Plus [Ordo Hereticus, Purgation Force](/40k/armies/imperial-agents/detachments/ordo-hereticus-purgation-force). The one with the weakest evidence.
The pairing itself is fine: a horde-clearing rule with a five-model floor patched by models that specialise in single high-value targets. But this is the one Imperial Agents detachment the Faction Pack does not print, amend or mention anywhere, so its whole rules text is mirror-sourced. Read its disclaimer before you commit.